4.7 Article

Antibacterial Secondary Metabolites from the Cave Sponge Xestospongia sp.

Journal

MARINE DRUGS
Volume 10, Issue 5, Pages 1037-1043

Publisher

MDPI AG
DOI: 10.3390/md10051037

Keywords

Xestospongia; polyacetylenes; antibacterial activity

Funding

  1. National Oceanic and Atmospheric Association [NOAA, NIUST] [NA16RU1496]
  2. USDA Agricultural Research Service [58-6408-2-0009]

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Chemical investigation of the cave sponge Xestospongia sp. resulted in the isolation of three new polyacetylenic long chain compounds along with two known metabolites. The structures of the new metabolites were established by NMR and MS analyses. The antibacterial activity of the new metabolites was also evaluated.

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