4.7 Article

New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae

Journal

MARINE DRUGS
Volume 10, Issue 2, Pages 306-318

Publisher

MDPI
DOI: 10.3390/md10020306

Keywords

Lobophytum michaelae; cembranolides; cytotoxicity

Funding

  1. National Science Council of Taiwan [NSC99-2628-B-110-002-MY3]

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Six new cembranolides, michaolides L-Q (1-6), and a known cembranolide, lobomichaolide (7) were isolated from the CH2Cl2 extract of the soft coral Lobophytum michaelae. Their structures were established by extensive spectral analysis. The anti-HCMV (human cytomegalovirus) activity of 1-7 and their cytotoxicity against selected cell lines were evaluated.

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