Journal
MARINE DRUGS
Volume 10, Issue 7, Pages 1566-1571Publisher
MDPI AG
DOI: 10.3390/md10071566
Keywords
pseudoalteromone; Pseudoalteromonas; anti-inflammatory; Lobophytum crassum; elastase
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Funding
- National Dong Hwa University
- National Museum of Marine Biology and Aquarium [10120022]
- Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University [00C-0302-05]
- National Science Council, Taiwan [NSC 101-2325-B-291-001, 101-2320-B-291-001-MY3, 98-2320-B-291-001-MY3]
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A novel 15C compound, pseudoalteromone B (1), possessing a novel carbon skeleton, was obtained from a marine bacterium Pseudoalteromonas sp. CGH2XX. This bacterium was originally isolated from a cultured-type octocoral Lobophytum crassum, that was growing in cultivating tanks equipped with a flow-through sea water system. The structure of 1 was established by spectroscopic methods. Pseudoalteromone B (1) displayed a modestly inhibitory effect on the release of elastase by human neutrophils.
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