Journal
MARINE DRUGS
Volume 10, Issue 11, Pages 2467-2480Publisher
MDPI AG
DOI: 10.3390/md10112467
Keywords
glycosphingolipid; ganglioside; GM4; starfish; Protoreaster nodosus
Categories
Ask authors/readers for more resources
Three new ganglioside molecular species, termed PNG-1, PNG-2A, and PNG-2B were isolated from pyloric caeca of the starfish Protoreaster nodosus. Their structures were elucidated using a combination of spectroscopic and chemical methods, and characterized as 1-O-[8-O-methyl-N-acetyl-alpha-neuraminosyl-(2 -> 3)-beta-galactopyranosyl]-ceramide for PNG-1, 1-O-[beta-galactofuranosyl-(1 -> 3)-alpha-galactopyranosyl-(1 -> 4)-8-O-methyl-N-acetyl-alpha-neuraminosyl-(2 -> 3)-beta-galactopyranosyl]-ceramide for PNG-2A, and 1-O-[beta-galactofuranosyl-(1 -> 3)-alpha-galactopyranosyl-(1 -> 9)-N-acetyl-alpha-neuraminosyl-(2 -> 3)-beta-galactopyr anosyl]-ceramide for PNG-2B. PNG-2A and PNG-2B represent the first GM4 elongation products in nature.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available