4.7 Article

Briareolate Esters from the Gorgonian Briareum asbestinum

Journal

MARINE DRUGS
Volume 10, Issue 8, Pages 1662-1670

Publisher

MDPI AG
DOI: 10.3390/md10081662

Keywords

Briareum asbestinum; octocoral; briarane; briareolate ester; human embryonic stem cell

Funding

  1. National Institutes of Health Grants [P41GM079597, P01GM085354]

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Two new briarane diterpenoids briareolate esters J (1) and K (2) were isolated from the methanolic extract of the octocoral Briareum asbestinum collected off the coast of Boca Raton, Florida. The structures of briaranes 1 and 2 were elucidated by interpretation of spectroscopic data. Briareolate ester K (2) showed weak growth inhibition activity against human embryonic stem cells (BG02).

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