4.7 Article

New 19-Oxygenated Steroids from the Soft Coral Nephthea chabrolii

Journal

MARINE DRUGS
Volume 10, Issue 6, Pages 1288-1296

Publisher

MDPI AG
DOI: 10.3390/md10061288

Keywords

Nephthea chabrolii; 19-oxygenated steroids; cytotoxicity; anti-HCMV

Funding

  1. National Science Council [NSC99-2628-B-110-002-MY3]
  2. Ministry of Education of Taiwan

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In order to search for novel bioactive substances from marine organisms, we investigated the acetone extract of the soft coral Nephthea chabrolii collected at San-Hsian-Tai, Taitong County, Taiwan. From this extract three new 19-oxygenated steroids, nebrosteroids N-P (1-3) were isolated. The structures of these compounds were elucidated by extensive spectroscopic analyses.

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