Journal
MARINE DRUGS
Volume 9, Issue 12, Pages 2705-2716Publisher
MDPI
DOI: 10.3390/md9122705
Keywords
soft coral; Lobophytum crassum; cytotoxicity
Categories
Funding
- National Science Council of Taiwan [NSC99-2628-B-110-002-MY3]
Ask authors/readers for more resources
Chemical investigation of the Dongsha Atoll soft coral Lobophytum crassum has afforded four new cembranoids, crassumols A-C (1-3) and 13-acetoxysarcophytoxide (4). The structures of these isolated compounds were elucidated by extensive NMR and HRESIMS experiments. The cytotoxicity and anti-HCMV (Human cytomegalovirus) activities of 1-4 were evaluated in vitro. Compound 4 exhibited cytotoxicity against A-549 (human lung carcinoma) cell line with an ED50 of 3.6 mu g/mL.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available