Journal
MARINE DRUGS
Volume 9, Issue 5, Pages 690-695Publisher
MDPI AG
DOI: 10.3390/md9050690
Keywords
actinomycete; Streptomyces microflavus; Hymeniacidon perlevis; deoxyuridine
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Funding
- Major State Basic Research Development Program of China (973 Program) [2009CB724700]
- Chinese Academy of Science [KSCX2-YW-G-073]
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One new nucleoside derivative, named 3-acetyl-5-methyl-2'-deoxyuridine (1), along with two known compounds 3,5-dimethyl-2'-deoxyuridine (2) and 3-methyl-2'-deoxyuridine (3), were isolated from the cultures of Streptomyces microflavus. This strain was an associated actinomycete isolated from the marine sponge Hymeniacidon perlevis collected from the coast of Dalian (China). Their structures were elucidated by detailed NMR and MS spectroscopic analysis as well as comparison with literature data.
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