4.7 Article

Statistical Research on Marine Natural Products Based on Data Obtained between 1985 and 2008

Journal

MARINE DRUGS
Volume 9, Issue 4, Pages 514-525

Publisher

MDPI AG
DOI: 10.3390/md9040514

Keywords

marine natural products; quantitative analysis; novel compounds

Funding

  1. Natural Science Foundation of China [40806059]
  2. Guangdong Provincial Natural Science Foundation [8151008901000014]
  3. National High-Tech Reasearch Program (863 Program) [2007AA09Z431, 2011AA090702]
  4. National Science and Technique Major Project [2009ZX09103-041, 201005022-2, 2009ZX10004-213, 2007FY210600]
  5. Key Science and Technique Research Project of Guangdong Province [2007A03260001, 2009A020101006, 2009B020600001, 2010B030600003]

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Since the 1960s, more than 20,000 compounds were discovered from marine organisms. In this paper we performed a quantitative analysis for the novel marine natural products reported between 1985 and 2008. The data was extracted mainly from the reviews of Faulkner and Blunt [1-26]. The organisms producing these marine natural products are divided into three major biological classes: marine microorganisms (including phytoplankton), marine algae and marine invertebrate. The marine natural products are divided into seven classes based on their chemical structure: terpenoids, steroids (including steroidal saponins), alkaloids, ethers (including ketals), phenols (including quinones), strigolactones, and peptides. The distribution and the temporal trend of these classes (biological classes and chemical structure classes) were investigated. We hope this article provides a comprehensive perspective on the research of marine natural products.

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