Journal
MARINE DRUGS
Volume 8, Issue 4, Pages 1323-1372Publisher
MDPI
DOI: 10.3390/md8041323
Keywords
marine; enzyme; bioprocess; bioreactor
Categories
Funding
- CSIR [09/096-0549-2K8-EMR-I]
- ICMR [45/54/2008/PHA/BMS]
- WB State [F-1/URS/Env Sc/848/2006]
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This review is a synopsis of different bioprocess engineering approaches adopted for the production of marine enzymes. Three major modes of operation: batch, fed-batch and continuous have been used for production of enzymes (such as protease, chitinase, agarase, peroxidase) mainly from marine bacteria and fungi on a laboratory bioreactor and pilot plant scales. Submerged, immobilized and solid-state processes in batch mode were widely employed. The fed-batch process was also applied in several bioprocesses. Continuous processes with suspended cells as well as with immobilized cells have been used. Investigations in shake flasks were conducted with the prospect of large-scale processing in reactors.
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