4.7 Review

Halogenated Indole Alkaloids from Marine Invertebrates

Journal

MARINE DRUGS
Volume 8, Issue 5, Pages 1526-1549

Publisher

MDPI
DOI: 10.3390/md8051526

Keywords

marine invertebrates; halogenated indole alkaloids; structure elucidation; bioactivity; C-13-NMR spectral data

Funding

  1. CNPq (The National Council for Scientific and Technological Development)
  2. FAPESP (Sao Paulo Research Foundation)

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This review discusses the isolation, structural elucidation, and biological activities of halogenated indole alkaloids obtained from marine invertebrates. Meridianins and related compounds (variolins, psammopemmins, and aplicyanins), as well as aplysinopsins and leptoclinidamines, are focused on. A compilation of the C-13-NMR spectral data of these selected natural indole alkaloids is also provided.

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