4.7 Article

Preparation and Characterization of Chitosan Poly(acrylic acid) Magnetic Microspheres

Journal

MARINE DRUGS
Volume 8, Issue 7, Pages 2212-2222

Publisher

MDPI
DOI: 10.3390/md8072212

Keywords

magnetic microsphere; magnetic separation; nanoparticles; chitosan poly(acrylic acid)

Funding

  1. National Natural Science Foundation of China (NSFC) [20876100, 20736004]
  2. National Basic Research Program of China [2009CB219904]
  3. State Key Lab. of Multiphase Complex Systems of the Chinese Academy of Science [2006-5]
  4. Key Lab. of Organic Synthesis of Jiangsu Prov.
  5. R&D Foundation of Nanjing Medical Univ. [NY0586]
  6. Post-doctoral Science Foundation of Jiangsu Prov.
  7. National Post-doctoral Science Foundation [20090451176]
  8. Commission of Science and Technology of Suzhou Municipality, China [YJS0917, SG0978]

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Spherical microparticles, capable of responding to magnetic fields, were prepared by encapsulating dextran-coated Fe3O4 nanoparticles into chitosan poly(acrylic acid) (PAA) microspheres template. The obtained magnetic microspheres were characterized by transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), X-ray powder diffraction (XRD), and thermogravimetry (TG). The results showed that the microspheres were formed and demonstrated magnetic behavior in an applied magnetic field. In addition, magnetite particles were well encapsulated and the composite particles have high magnetite content, which was more than 40%.

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