Journal
MARINE DRUGS
Volume 8, Issue 4, Pages 941-949Publisher
MDPI
DOI: 10.3390/md8040941
Keywords
phenolic bisabolane-type sesquiterpenoid; Aspergillus sp.; gorgonian Dichotella gemmacea
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Funding
- National Natural Science Foundation of China [40976077, 30901879, 40776073]
- Ministry of Education of China [20090132110002]
- Ministry of Science and Technology of China [2007FY210500]
- Key Laboratory of Marine Drugs (Ocean University of China), Ministry of Education [KLMD (OUC) 200801]
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Three new phenolic bisabolane-type sesquiterpenoids: (+)-methyl sydowate (1), 7-deoxy-7,14-didehydrosydonic acid (2), and 7-deoxy-7,8-didehydrosydonic acid (3), together with two known fungal metabolites were isolated from the fermentation broth of a marine-derived fungus Aspergillus sp., which was isolated in turn from a gorgonian Dichotella gemmacea collected from the South China Sea. Their structures were elucidated by combined spectroscopic methods, and the structure of 1 was further confirmed by single-crystal X-ray data.
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