Journal
MAMMALIAN GENOME
Volume 23, Issue 9-10, Pages 632-640Publisher
SPRINGER
DOI: 10.1007/s00335-012-9427-x
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Funding
- MRC [MC_U142684172, MC_U142684175] Funding Source: UKRI
- Medical Research Council [MC_U142684172, MC_U142684175] Funding Source: researchfish
- Medical Research Council [MC_U142684175, MC_U142684172] Funding Source: Medline
- NHGRI NIH HHS [U54 HG006348] Funding Source: Medline
- NIH HHS [U42 OD011174] Funding Source: Medline
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Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse production and phenotyping.
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