Journal
MAMMALIAN GENOME
Volume 23, Issue 9-10, Pages 641-652Publisher
SPRINGER
DOI: 10.1007/s00335-012-9428-9
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Funding
- Medical Research Council [MC_U142684172, MC_U142684171, MC_U142684175] Funding Source: Medline
- NHGRI NIH HHS [U54 HG006370] Funding Source: Medline
- MRC [MC_U142684172, MC_U142684175, MC_U142684171] Funding Source: UKRI
- Medical Research Council [MC_U142684172, MC_U142684175, MC_U142684171] Funding Source: researchfish
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The International Mouse Phenotyping Consortium (IMPC) (http://www.mousephenotype.org) will reveal the pleiotropic functions of every gene in the mouse genome and uncover the wider role of genetic loci within diverse biological systems. Comprehensive informatics solutions are vital to ensuring that this vast array of data is captured in a standardised manner and made accessible to the scientific community for interrogation and analysis. Here we review the existing EuroPhenome and WTSI phenotype informatics systems and the IKMC portal, and present plans for extending these systems and lessons learned to the development of a robust IMPC informatics infrastructure.
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