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JD Rothstein et al.
NATURE (2005)
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
E Storkebaum et al.
NATURE NEUROSCIENCE (2005)
Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice
D Kieran et al.
NATURE MEDICINE (2004)
Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis
PA Jonsson et al.
BRAIN (2004)
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
AL Nishimura et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar et al.
NATURE GENETICS (2004)
DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)
YZ Chen et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Message and protein-level elevation of tumor necrosis factor α(TNFα) and TNFα-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis
K Hensley et al.
NEUROBIOLOGY OF DISEASE (2003)
Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice
S Tobisawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Mutant dynactin in motor neuron disease
I Puls et al.
NATURE GENETICS (2003)
Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature
J Wang et al.
HUMAN MOLECULAR GENETICS (2003)
Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice
M Mattiazzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Minocycline slows disease progression in a mouse model of arnyotrophic lateral sclerosis
J Kriz et al.
NEUROBIOLOGY OF DISEASE (2002)
Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site
J Wang et al.
NEUROBIOLOGY OF DISEASE (2002)
Minocycline delays disease onset and mortality in a transgenic model of ALS
L Van Den Bosch et al.
NEUROREPORT (2002)
A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections
CW Jung et al.
JOURNAL OF NEUROSCIENCE METHODS (2002)
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
DS Howland et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
M Göttlicher et al.
EMBO JOURNAL (2001)
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
Y Yang et al.
NATURE GENETICS (2001)
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
S Hadano et al.
NATURE GENETICS (2001)
Effects of riluzole on N-methyl-D-aspartate-induced tyrosine phosphorylation in the rat hippocampus
A Peyclit et al.
BRAIN RESEARCH (2001)
Formation of high molecular weight complexes of mutant Cu,Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
JA Johnston et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis
G Ochs et al.
AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS (2000)