Journal
MAGNETIC RESONANCE IN MEDICINE
Volume 63, Issue 5, Pages 1144-1153Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/mrm.22361
Keywords
parallel imaging; 7 Tesla; fMRI; multislice excitation; GRAPPA
Funding
- NIH [P41 RR08079, R01 MH070800, R01 EB008645, R01 EB000331, EB 000513, CA 76535, P30 NS057091]
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Parallel imaging in the form of multiband radiofrequency excitation, together with reduced k-space coverage in the phase-encode direction, was applied to human gradient echo functional MRI at 7 T for increased volumetric coverage and concurrent high spatial and temporal resolution. Echo planar imaging with simultaneous acquisition of four coronal slices separated by 44mm and simultaneous 4-fold phase-encoding undersampling, resulting in 16-fold acceleration and up to 16-fold maximal aliasing, was investigated. Task/stimulus-induced signal changes and temporal signal behavior under basal conditions were comparable for multiband and standard single-band excitation and longer pulse repetition times. Robust, whole-brain functional mapping at 7 T, with 2 x 2 x 2mm(3) (pulse repetition time 1.25 sec) and 1 x 1 x 2mm(3) (pulse repetition time 1.5 sec) resolutions, covering fields of view of 256 x 256 x 176mm(3) and 192 x 172 x 176mm(3), respectively, was demonstrated with current gradient performance. Magn Reson Med 63:1144-1153, 2010. (C) 2010 Wiley-Liss, Inc.
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