Journal
MAGNETIC RESONANCE IN MEDICINE
Volume 59, Issue 2, Pages 229-235Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/mrm.21490
Keywords
edema; infarction; T2; ACUT(2)E; ACUTE; C-TIDE; myocardium; heart
Funding
- Intramural NIH HHS Funding Source: Medline
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ACUT(2)E TSE-SSFP is a hybrid between steady state free precession (SSFP) and turbo spin echo (TSE) for bright-blood T2-weighted imaging with signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) similar to dark-blood TSE. TSE-SSFP uses a segmented SSFP readout during diastole with 180 pulses following a 90 preparation. The 180 refocusing pulses make TSE-SSFP similar to TSE but TSE-SSFP uses gradient moment nulling, whereas TSE uses gradient crushing. TSE-SSFP produced T2-weighted images with minimal T1 weighting. TSE-SSFP and TSE had similar SNR (155.9 +/- 6.0 vs 160.9 +/- 7.0; P = NS) for acute myocardial infarction (MI) and twice the SNR of T2-prepared SSFP (73.1 +/- 3.4, P < 0.001). TSE-SSFP and TSE had approximately double the CNR of T2-prepared SSFP for differentiating acute MI from normal myocardium. Imperfect blood suppression, present in all animals on some TSE images, was a problem eliminated by TSE-SSFP and T2-prepared SSFP.
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