4.2 Article

A simple flowcell for reaction monitoring by NMR

Journal

MAGNETIC RESONANCE IN CHEMISTRY
Volume 48, Issue 7, Pages 516-522

Publisher

WILEY
DOI: 10.1002/mrc.2610

Keywords

NMR; H-1; flowcell; kinetics; reaction monitoring

Funding

  1. Engineering and Physical Sciences Research Council [EP/D05592X, EP/E057888/1]
  2. AstraZeneca
  3. EPSRC [EP/E057888/1] Funding Source: UKRI
  4. Engineering and Physical Sciences Research Council [EP/E057888/1] Funding Source: researchfish

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A simple, cheap and flexible flowcell based on a standard 5 mm NMR tube, designed for the monitoring of reactions but of wide applicability, is described. No modification of the NMR instrument is needed, allowing the system to be employed with any conventional NMR probe and magnet. The system is robust and economical in use of reagents, and can be used for studying both homogeneous and heterogeneous reactions. Copyright (C) 2010 John Wiley & Sons, Ltd.

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