Journal
MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICA
Volume 21, Issue 2, Pages 241-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.mric.2013.02.004
Keywords
Glioma; Glioblastoma; MacDonald criteria; Response assessment; Radiation necrosis; Pseudoresponse; MR imaging; Imaging biomarkers
Funding
- Bracco Diagnostics
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Although conventional contrast-enhanced MR imaging remains the standard-of-care imaging method in the posttreatment evaluation of gliomas, recent developments in therapeutic options such as chemoradiation and antiangiogenic agents have caused the neuro-oncology community to rethink traditional imaging criteria. This article highlights the latest recommendations. These recommendations should be viewed as works in progress. As more is learned about the pathophysiology of glioma treatment response, quantitative imaging biomarkers will be validated within this context. There will likely be further refinements to glioma response criteria, although the lack of technical standardization in image acquisition, postprocessing, and interpretation also need to be addressed.
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