Journal
MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICA
Volume 18, Issue 3, Pages 337-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.mric.2010.08.013
Keywords
Fat quantification; Magnetic resonance imaging; Hepatic steatosis; Quantitative biomarkers
Funding
- NIDDK NIH HHS [R01 DK083380-02, R01 DK088925-02, R01 DK083380-01A1, R01 DK088925, R01 DK088925-01, R01 DK083380] Funding Source: Medline
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Intracellular fat accumulation is common feature of liver disease. Intracellular fat (steatosis) is the histologic hallmark of nonalcoholic fatty liver disease but also may occur with alcohol abuse, viral hepatitis, HIV and genetic lipodystrophies, and chemotherapy. This article reviews emerging MR imaging techniques that attempt to quantify liver fat. The content provides an overview of fatty liver disease and diseases where fat is an important disease feature. Also discussed is the current use and limitation of nontargeted biopsy in diffuse liver disease and why quantitative noninvasive biomarkers of liver fat would be beneficial.
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