Journal
MAGNETIC RESONANCE IMAGING
Volume 27, Issue 5, Pages 631-636Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.mri.2008.10.007
Keywords
Diffusion tensor imaging; High spatial resolution; Whole brain; Tractography; Commissural; Projection; Association pathways; Icosahedral
Funding
- NIH-NINDS [R01 NS052505-03]
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The mapping of the human brain white matter fiber networks relative to deep subcortical and cortical gray matter requires high spatial resolution which is challenged by the low signal-to-noise ratio. The purpose of this short report wits to introduce a whole brain high spatial resolution diffusion tensor imaging (DTI) protocol that enabled for the first time the mapping of corticopontocerebellar, frontostriatal and thalamofrontal fiber pathways in addition to other limbic, commissural, association and projection white matter pathways relative to the segmented deep gray (e.g., caudate nuclei) and the cortical lobes. Our DTI acquisition protocol and analysis strategy provide important template for brain-behavior research and for teaching brain mapping and are clinically affordable for patient comfort. (C) 2009 Elsevier Inc. All rights reserved.
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