Journal
MACROMOLECULAR RESEARCH
Volume 18, Issue 8, Pages 793-799Publisher
SPRINGER
DOI: 10.1007/s13233-010-0803-7
Keywords
magnetite; radical copolymerization; magnetic marker; immunoassay
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Funding
- Pusan National University
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Polymer-coated magnetite fine particles with carboxyl groups were developed for applications as an immunoassay magnetic marker. The magnetite composites were prepared using the following method. A hydrophilic macromer with a polymerizable vinyl group at the terminal was adsorbed on the surface of the magnetite fine particles. Subsequently, a hydrophilic vinyl monomer with a carboxyl group and a crosslinking agent were added to carry out a copolymerization reaction. The resulting magnetite composite particles were dispersed stably in an aqueous medium. The composite particles exhibited high antibody binding ability and high-sensitive magnetic properties suitable for applications as magnetic markers.
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