Journal
MACROMOLECULAR RAPID COMMUNICATIONS
Volume 34, Issue 18, Pages 1464-1470Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/marc.201300494
Keywords
dextran; hydrogels; self-healing
Categories
Funding
- National Natural Science Foundation of China [51073127, 51173144, 21105079]
- Research Fund for the Doctoral Program of Higher Education of China [20100201110040]
- Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
- Fundamental Research Funds for the Central Universities [2009-0109-08140018, 2011-0109-08143038]
- Ministry of Science and Technology of China
- Shaanxi Province
- New Research Support Project of Xi'an Jiaotong University, P.R. China
- Major International Joint Research Program of China [11120101002]
- National 111 Project of China [B06024]
- International Science & Technology Cooperation Program of China [2013DFG02930]
Ask authors/readers for more resources
A dextran-based self-healing hydrogel is prepared by reversible Diels-Alder reaction under physiological conditions. Cytocompatible fulvene-modified dextran as main polymer chains and dichloromaleic-acid-modified poly(ethylene glycol) as cross-linkers are used. Both macro- and microscopic observation as well as the rheological recovery test confirm the self-healing property of the dextran-l-poly(ethylene glycol) hydrogels (l means linked-by). In addition, scanning electrochemical microscopy is used to qualitatively and quantitatively in situ track the self-healing process of the hydrogel for the first time. It is found that the longitudinal depth of scratch on hydrogel surface almost completely healed at 37 degrees C after 7 h. This work represents a facile approach for fabrication of polysaccharide self-healing hydrogel, which can be potentially used in several biomedical fields.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available