Journal
MACROMOLECULAR RAPID COMMUNICATIONS
Volume 30, Issue 7, Pages 539-542Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/marc.200800634
Keywords
collagen; electrospinning; fibers; scaffold; structure; tissue engineering
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Funding
- CWRU Innovation Incentive Fellowship
- National Institute of Arthritis and Musculoskeletal and Skin Diseases
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Nanofiber scaffolds of collagen have been fabricated via electrospinning using benign solvent systems as a replacement for 1,1,1,3,3,3 hexafluoro-2-propanol. Simple binary mixtures of phosphate-buffered saline and ethanol have been found to be highly effective for electrospinning. FTIR spectra suggest that the triple helical structure of collagen was conserved after dissolution and electrospinning. Crosslinking of the electrospun collagen scaffolds was achieved with standard methods.
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