Journal
MACROMOLECULAR RAPID COMMUNICATIONS
Volume 30, Issue 4-5, Pages 299-315Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/marc.200800740
Keywords
biological applications of polymers; biomimetic inflammation; polysulfides; stimuli-sensitive polymers
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Funding
- EPSRC [EP/C543564/1]
- Alexander von Humboldt Foundation
- Engineering and Physical Sciences Research Council [EP/C543572/1, EP/C543564/1] Funding Source: researchfish
- EPSRC [EP/C543572/1] Funding Source: UKRI
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Sulfur(II)-containing polymers (polysulfides) combine flexible synthetic and processing techniques with a unique responsiveness to oxidants. Here, the polysulfide oxidative sensitivity is put into the biological context of the development of new anti-inflammatory therapies - the development of new anti-inflammatory methodologies, adopted interactions and the minimisation of foreign-body reactions - through the review of 50 years of research on polysulfide synthetic methodologies. Attention is paid to the identification of the most flexible and robust preparative techniques.
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