Banded Spherulitic Morphology in Blends of Poly (propylene fumarate) and Poly(ε-caprolactone) and Interaction with MC3T3-E1 Cells

The thermal properties, morphological development, crystallization behavior, and miscibility of semicrystalline PCL and its 25, 50, and 75 wt% blends with amorphous PPF in spin-coated thin films crystallized at various crystallization temperatures (Tc) from 25 to 52 degrees C are investigated. The surface roughness of PPF/PCL (?PCL = 75%) films increases with increasing Tc and consequently the adsorption of serum proteins is also increased. No significant variance is found in surface hydrophilicity or in mouse MC3T3-E1 cell attachment, spreading, and proliferation on PPF/PCL (?PCL = 75%) films crystallized isothermally at 25, 37, and 45 degrees C, because of low ridge height, nonuniformity in structures, and PPF surface segregation.