4.4 Article

pH-Responsive Vesicles from a Schizophrenic Diblock Copolymer

Journal

MACROMOLECULAR CHEMISTRY AND PHYSICS
Volume 211, Issue 14, Pages 1530-1537

Publisher

WILEY-BLACKWELL
DOI: 10.1002/macp.201000022

Keywords

RAFT; schizophrenic block copolymer; self-assembly; vesicle

Funding

  1. EPSRC
  2. Leverhulme Trust
  3. Royal Society
  4. Advantage West Midlands (AWM)
  5. European Regional Development Fund (ERDF)
  6. Welcome Trust [055663/Z/98/Z]
  7. Engineering and Physical Sciences Research Council [EP/G004897/1] Funding Source: researchfish
  8. EPSRC [EP/G004897/1] Funding Source: UKRI

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A novel tertiary amine and amino acid-based schizophrenic pH-responsive block copolymer, PDEA-b-PAP, has been synthesized by RAFT polymerization. By directly dissolving this copolymer in acid or basic aqueous solution block copolymer vesicles with switchable coronas and membranes were prepared. These novel assemblies were characterized using TEM, DLS, zeta potential, and SLS analysis.

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