Journal
MACROMOLECULAR BIOSCIENCE
Volume 13, Issue 12, Pages 1640-1647Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mabi.201300272
Keywords
mechanical properties; stimuli-sensitive polymers; structure-property relations; thermosets; thin films
Funding
- National Science Foundation [1114211, 2011113646]
- National Institutes of Health/National Institute of Biomedical Imaging and Bioengineering [R01EB000462]
- Defense Advanced Research Projects Agency (DARPA)/MTO Young Faculty Award (YFA) [D13AP00049]
- Directorate For Engineering
- Div Of Industrial Innovation & Partnersh [1114211] Funding Source: National Science Foundation
Ask authors/readers for more resources
Neural interfaces provide an electrical connection between computers and the nervous system: current penetrating devices are orders-of-magnitude stiffer than surrounding tissue. In this work, recent efforts in softening electronics and utilize thiol-ene and thiol-epoxy click reactions are built upon to incorporate fluid-sensitive hydrogen bonding into smart substrates for high electrode density neural interfaces. The modulus of these substrates drops more than two orders of magnitude in response to physiological conditions, despite fluid uptake of less than 6%, and can be tuned by the covalent crosslink density and degree of hydrogen bonding in the polymer network. Intracortical and intrafascicular electrode arrays are fabricated and characterized with impedance spectroscopy and cyclic voltammetry.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available