Journal
MACROMOLECULAR BIOSCIENCE
Volume 13, Issue 12, Pages 1681-1688Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mabi.201300264
Keywords
ATRP; biomaterials; graft copolymers; hemocompatibility; polyurethanes; zwitterionic polymer
Funding
- Ministry of Science and Technology of China [2013DFG52040, 2008DFA51170]
- Ph.D. Programs Foundation of Ministry of Education of China [20120032110073]
- Program of Introducing Talents of Discipline to Universities of China [B06006]
Ask authors/readers for more resources
The hemocompatibility of polycarbonateurethane (PCU) surfaces is improved by decoration with poly(poly(ethylene glycol) methacrylate) (poly(PEGMA)) and zwitterionic poly(3-((2-(methacryloyloxy)ethyl)dimethylammonio)propane-1-sulfonate) (poly(DMAPS)) blocks providing a novel multicomb structure obtained by application of surface-initiated atom transfer radical polymerization (s-ATRP) conditions. The PCU-poly(PEGMA-g-DMAPS) surface shows high hydrophilicity with a low contact angle of 20.6 +/- 1.8 degrees, while PCU-poly(PEGMA-b-DMAPS) surface exhibitsed a contact angle of 30.5 +/- 2.6 degrees. Furthermore, PCU-poly(PEGMA-g-DMAPS) surface shows very low platelet adsorption indicating that multicomb structure modified PCUs are preferred candidate materials for blood-contacting materials.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
