Journal
MACROMOLECULAR BIOSCIENCE
Volume 13, Issue 1, Pages 9-27Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mabi.201200222
Keywords
biomolecular recognition; glyco-nanoparticles; glycopolymers; vaccines
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With advances in polymerization techniques as well as selective chemical modification of carbohydrates, glycopolymers and glyco-nanoparticles are emerging as an important class of materials with tailored properties or novel nanotechnology-based platforms for a number of applications. The field of the so-called glyco-nanotechnology is starting to show some promises for future clinical applications. Glyco-nanoparticles, due to their versatile nature, could offer a platform for the design of carbohydrate-based vaccines and possibly allow the development of new single-dose vaccines in disease areas of unmet need. This paper surveys the emerging roles of carbohydrate-based polymeric and nanomaterials for biomolecular recognition processes and vaccine development.
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