Journal
MACROMOLECULAR BIOSCIENCE
Volume 12, Issue 1, Pages 61-66Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mabi.201100268
Keywords
biocompatibility; graphene oxide; layer-by-layer assembly; nanotechnology; yeast cells
Funding
- Korea Science and Engineering Foundation
- Ministry of Education, Science and Technology [R31-2008-000-20012-0, 2010-0001953, 2010-0029434]
- Korea Research Foundation
- Korean Government (MOEHRD) [KRF-2008-313-C00496]
- Ministry of Health & Welfare, Republic of Korea [A091047]
- National Research Foundation of Korea (NRF)
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The first example of the encapsulation of living yeast cells with multilayers of GO nanosheets via LbL self-assembly is reported. The GO nanosheets with opposite charges are alternatively coated onto the individual yeast cells while preserving the viability of the yeast cells, thus affording a means of interfacing graphene with living yeast cells. This approach is expanded by integrating other organic polymers or inorganic nanoparticles to the cells by hybridizing the entries with GO nanosheets through LbL self-assembly. It is demonstrated that incorporated iron oxide nanoparticles can deliver magnetic properties to the biological systems, allowing the integration of new physical and chemical functions for living cells with a combination of GO nanosheets.
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