Journal
MACROMOLECULAR BIOSCIENCE
Volume 10, Issue 3, Pages 231-238Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mabi.200900349
Keywords
aqueous solubility; biohybrid materials; helical wrapping; polysaccharides; single-walled carbon nanotubes
Funding
- National Science Foundation [CMMI-0709121, CCF-0523858]
- National Research Initiative of the USDA-CSREES [2005-35603-15902]
- Arkansas Agricultural Experiment Station
- Arkansas Biosciences Institute
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A facile and easily reproducible technique for assembling biohybrid nanoparticles is a core feature that is highly desired for biomedical applications, considering the nature and limited lifespan of the biopolymers used. Here we show a simple and effective method to enfold single-walled carbon nanotubes (SWNTs) using an anionic polysaccharide, dextran sulfate. After their interactions, SWNTs were rendered dispersible in aqueous solution and were shortened and unbundled to their basic dimension. Atomic force microscopy analysis was extensively employed to elucidate the mechanism of their interfacing. This biohybrid nanoparticle holds promise for biological and biomedical applications due to the synergistic unique properties of SWNTs and dextran sulfate.
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