Journal
LUPUS
Volume 27, Issue 12, Pages 1881-1897Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0961203318793206
Keywords
Nephritis; stem cells; systemic lupus erythematosus
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Lupus nephritis (LN), a common manifestation of systemic lupus erythematosus (SLE), accounts for significant morbidity and mortality in SLE patients. Since the available standard therapies and biologic agents for LN are yet to achieve the desired response and have considerable secondary effects, stem cell therapy has now emerged as a new approach. This therapy involves the transplantation of hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs). Our current review will highlight the progress of stem cell therapy for LN, along with the challenges encountered and the future direction of this approach.
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