Journal
LUNG CANCER
Volume 69, Issue 1, Pages 123-126Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.lungcan.2010.04.022
Keywords
Ground-glass opacity; Follow-up; Bronchioloalveolar carcinoma; Lung adenocarcinoma; CT lung neoplasms; PET
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The natural chronologic evolution of a lung cancer manifesting as a pure ground-glass opacity (GGO) nodule on CT scans still remains to be elucidated. Therefore, it is sometimes difficult to determine proper follow-up examinations, particularly in case of GGO nodule growing slowly on serial CT scans. In the current case, we demonstrate serial morphologic (CT) and metabolic (F-18-FDG PET) imaging findings in a case of adenocarcinoma, where stepwise progression from a focal pure GGO nodule (presumed atypical adenomatous hyperplasia [AAH] or bronchioloalveolar carcinoma [BAC]) eventually to an invasive adenocarcinoma was clearly depicted for more than 10-year follow-up period. This case seems to be useful for the prediction of tumor growth pattern and aggressiveness of malignant pure GGO nodules. In addition, the evolving process of this case may suggest a guideline for planning an appropriate follow-up examination and management in such cases. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
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