Journal
LUNG CANCER
Volume 68, Issue 1, Pages 10-15Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.lungcan.2009.11.004
Keywords
Lung cancer; Cancer pain; Opioids; Palliative care; Pain syndromes; Breakthrough pain; Opioid switching
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This review analyses the characteristics of the principal pain syndromes associated with lung cancer, their physiopathology and causes, and provides updated information on available treatments. Pain associated with lung cancer is characterized by multiple expressions, due to either the progression of disease and/or induced by oncological treatment. The analgesic treatment is principally based on the use of opioids. Other than the oral route, which is the preferred one, alternative modalities to administer opioids may be helpful in different clinical circumstances. According to the opioid response, other routes and other opioids, may improve the balance between analgesia and adverse effects providing the best individual response to a specific opioid drug. More complex strategies, such as interventional procedures, are seldom necessary and require an appropriate selection of patients. (C) 2009 Published by Elsevier Ireland Ltd.
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