Related references
Note: Only part of the references are listed.Targeting B-Cell Receptor Signaling for Anticancer Therapy: The Bruton's Tyrosine Kinase Inhibitor Ibrutinib Induces Impressive Responses in B-Cell Malignancies
Adrian Wiestner
JOURNAL OF CLINICAL ONCOLOGY (2013)
Bruton Tyrosine Kinase Inhibitor Ibrutinib (PCI-32765) Has Significant Activity in Patients With Relapsed/Refractory B-Cell Malignancies
Ranjana H. Advani et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo
Sabine Ponader et al.
BLOOD (2012)
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies
Andreas Agathangelidis et al.
BLOOD (2012)
Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia
Adrian Wiestner
BLOOD (2012)
The B-cell receptor signaling pathway as a therapeutic target in CLL
Jennifer A. Woyach et al.
BLOOD (2012)
The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia
Martin F. M. de Rooij et al.
BLOOD (2012)
Novel Targeted Agents and the Need to Refine Clinical End Points in Chronic Lymphocytic Leukemia
Bruce D. Cheson et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling
Marcus Duehren-von Minden et al.
NATURE (2012)
Novel Agents and Emerging Strategies for Targeting the B-Cell Receptor Pathway in CLL
Dimitar G. Efremov et al.
MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES (2012)
The lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia
Yair Herishanu et al.
BLOOD (2011)
A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease
Davide Bagnara et al.
BLOOD (2011)
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
Sarah E. M. Herman et al.
BLOOD (2011)
Investigating the role of CD38 and functionally related molecular risk factors in the CLL NOD/SCID xenograft model
Semra Aydin et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2011)
The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells
Betty Y. Chang et al.
ARTHRITIS RESEARCH & THERAPY (2011)
Nurture versus Nature: The Microenvironment in Chronic Lymphocytic Leukemia
Jan A. Burger
HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM (2011)
A novel Rag2-/-γc-/--xenograft model of human CLL
Maria Teresa Sabrina Bertilaccio et al.
BLOOD (2010)
Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia
Jonathan W. Friedberg et al.
BLOOD (2010)
The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Eμ-TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling
Mirza Suljagic et al.
BLOOD (2010)
Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia
Maike Buchner et al.
BLOOD (2010)
The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia
Ulf Klein et al.
CANCER CELL (2010)
被撤回的出版物: Expanded and highly active proliferation centers identify a histological subtype of chronic lymphocytic leukemia (accelerated chronic lymphocytic leukemia) with aggressive clinical behavior (Retracted Article. See vol 95, pg 1620, 2010)
Eva Gine et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2010)
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy
Lee A. Honigberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Antigens in chronic lymphocytic leukemia-Implications for cell origin and leukemogenesis
Anders Rosen et al.
SEMINARS IN CANCER BIOLOGY (2010)
Expression and function of toll like receptors in chronic lymphocytic leukaemia cells
Marta Muzio et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
Chronic lymphocytic leukemia microenvironment: shifting the balance from apoptosis to proliferation
Silvia Deaglio et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2009)
The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells
Mohammad Luqman et al.
BLOOD (2008)
The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells
Pablo G. Longo et al.
BLOOD (2008)
Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA
Charles C. Chu et al.
BLOOD (2008)
Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy
Marta Muzio et al.
BLOOD (2008)
Microenvironmental influences in chronic lymphocytic leukaemia: the role of antigen stimulation
P. Ghia et al.
JOURNAL OF INTERNAL MEDICINE (2008)
A novel nonobese diabetic/severe combined immunodeficient xenograft model for chronic lymphocytic leukemia reflects important clinical characteristics of the disease
Jan Duerig et al.
CANCER RESEARCH (2007)
Cell proliferation and death: Forgotten features of chronic lymphocytic leukemia B cells
Nicholas Chiorazzi
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY (2007)
Reversible anergy of sIgM-mediated signaling in the two subsets of CLL defined by VH-gene mutational status
C. Ian Mockridge et al.
BLOOD (2007)
BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-κB pathway
Tomoyuki Endo et al.
BLOOD (2007)
Molecular transfer of CD40 and OX40 ligands to leukemic human B cells induces expansion of autologous tumor-reactive cytotoxic T lymphocytes
E Biagi et al.
BLOOD (2005)
In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells
BT Messmer et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia
BT Messmer et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia
G Tobin et al.
BLOOD (2004)
The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma
A Rosenwald et al.
CANCER CELL (2003)
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression
R Bichi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Survival of leukemic B cells promoted by engagement of the antigen receptor
A Bernal et al.
BLOOD (2001)
Share Paper
