Journal
LETTERS IN ORGANIC CHEMISTRY
Volume 7, Issue 6, Pages 472-474Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157017810791824946
Keywords
Pyrrolizidines; ionic liquid; isatine; diastereoselective; 1,3-dipolar cycloaddition
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Funding
- Research Council of Shahid Beheshti University
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Pyrrolizidines were synthesized from 1,3-dipolar cycloaddition of N-substituted isatins, proline, and olefins. The highly diastereoselective and regioselective one-pot three-component cyclocondensation products were obtained in the presence of ionic liquids such as 1-buthyl-3-methlylimidazolium bromide.
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