4.2 Article

A Short Route to [1,2,3]-Triazolyl Coumarin and Quinolone Derivatives by Cu(I) Catalyzed 1,3-Dipolar Cycloaddition and Fluorescence Studies

Journal

LETTERS IN ORGANIC CHEMISTRY
Volume 6, Issue 1, Pages 82-87

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157017809787003250

Keywords

1,3-dipolar cycloaddition; 6 and 7-azidocoumarin; 6-azidoquinolone; [1,2,3] triazole; phenyl acetylene; fluorescence

Funding

  1. DST (New Delhi)
  2. CSIR (New Delhi)

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Hitherto unreported [1,2,3]-triazolyl coumarin and quinolone derivatives in good to excellent yields have been expediently synthesized from 6- and 7-azidocoumarin and 6-azidoquinolone by copper (I) catalyzed 1,3-dipolar cycloaddition. Azidocoumarins and azidoquinolones were in turn prepared efficiently from the corresponding amines. Fluorescence studies of the newly synthesized [1,2,3]-triazolyl coumarin and quinolone derivatives are also described.

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