Journal
LETTERS IN ORGANIC CHEMISTRY
Volume 6, Issue 5, Pages 381-383Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157017809788681284
Keywords
5-Aminopyrazole; 3-(1H-indol-3-yl)-3-oxopropanenitrile; Benzaldehyde; Indolylpyrazolo[3,4-b]pyridine; Three-component reaction; Solvent-free procedure; Microwave
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New 4-(1H-indol-3-yl)-6-arylpyrazolo[3,4-b] pyridines 7 have been prepared in a solvent-free three-component reaction induced by microwave from 5-aminopyrazole 1, benzaldehydes 2 and 3-indolyl-3-oxopropanenitrile 5. These compounds were also obtained by means of the reaction of aminopyrazole 1 with benzylidene-derivatives of 3-(1H-indol-3- yl)-3-oxopropanenitrile 6, prepared in the reaction of 3-(1H-indol-3-yl)-3-oxopropanenitrile and aldehydes.
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