Journal
LEARNING & MEMORY
Volume 16, Issue 11, Pages 676-681Publisher
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/lm.1569309
Keywords
-
Categories
Funding
- NIH [R01 DC04682]
Ask authors/readers for more resources
Odor preference learning in the neonate rat follows pairing of odor input and noradrenergic activation of beta-adrenoceptors. Odor learning is hypothesized to be supported by enhanced mitral cell activation. Here a mechanism for enhanced mitral cell signaling is described. Theta bursts in the olfactory nerve (ON) produce long-term potentiation (LTP) of glomerular excitatory postsynaptic potentials (EPSPs) and of excitatory postsynaptic currents (EPSCs) in the periglomerular (PG) and external tufted (ET) cells. Theta bursts paired with beta-adrenoceptor activation significantly elevate mitral cell (MC) calcium. Juxtaglomerular inhibitory network depression by beta-adrenoceptor activation appears to increase calcium in MCs in response to theta burst stimulation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available