4.4 Article

TiO2 nanoparticle enhanced photodynamic inhibition of pathogens

Journal

LASER PHYSICS LETTERS
Volume 7, Issue 8, Pages 607-612

Publisher

IOP Publishing Ltd
DOI: 10.1002/lapl.201010030

Keywords

phototherapy; titanium dioxide; methylene blue; LED-light

Funding

  1. Development of High School Potential [N2.1.1/4989, N2.2.1.1/2950, FP7-ICT-2007-2, N224014]
  2. Program of RF Scientific and Pedagogical Personnel of Innovative Russia

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Uncovered TiO2 nanoparticles were shown to provide bactericidal activity against the three pathogens: Staphylococcus aureus, Escherichia coli, and Candida albicans at irradiation by blue (405 nm) light. It was found that the combination of a photocatalyst (TiO2-nanoparticles) and a photosensitizer (methylene blue) at two-wavelength irradiation with blue (405 nm) and red (625 nm) light provides a pronounced antimicrobial effect.

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