Journal
LARYNGOSCOPE
Volume 121, Issue 9, Pages 2001-2003Publisher
WILEY-BLACKWELL
DOI: 10.1002/lary.21793
Keywords
Pediatric sinonasal malignancies
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Objectives: Sinonasal malignancies in children are rare, histologically diverse tumors that present diagnostic and management challenges. The purpose of this study is to review the experience of a single cancer center in the management of pediatric sinonasal malignancies. Study Design: Retrospective review. Methods: Retrospective chart review. Results: Forty-four patients were identified. The median age was 12 years (range: 2-17), 54% were female, and the maxillary sinus was the most common primary site. Facial swelling and pain were the most common presenting complaints. Thirty-four patients (76%) in this series had paranasal sinus sarcomas, three patients had esthesioneuroblastomas, and eight patients had carcinomas. The 5-year overall survival, disease-specific survival, and recurrence rate for the entire group was 71%, 81%, and 43%, respectively. Conclusions: Pediatric sinonasal malignancies are rare, locally aggressive tumors associated with nonspecific signs and symptoms. Multimodality treatment can result in 5-year overall and disease-specific survival rates of over 70%. A multidisciplinary team approach is essential to optimize outcomes and limit the morbidity of treatment.
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