Journal
LANGMUIR
Volume 28, Issue 4, Pages 2015-2022Publisher
AMER CHEMICAL SOC
DOI: 10.1021/la204426q
Keywords
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Funding
- European Commission [BeNatural/NMP4-CT-2006-033256]
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Biocompatible hydrogels are of high interest as a class of biomaterials for tissue engineering, regenerative medicine, and controlled drug delivery. These materials offer three-dimensional scaffolds to support the growth of cells and development of hierarchical tissue structures. Fmoc-peptides were previously demonstrated as attractive building blocks for biocompatible hydrogels. Here, we further investigate the biophysical properties of Fmoc-peptide-based hydrogels for medical applications. We describe the structural and thermal properties of these Fmoc-peptides, as well as their self-assembly process. Additionally, we study the role of interactions between aromatic moieties in the self-assembly process and on the physical and structural properties of the hydrogels.
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