Journal
LANGMUIR
Volume 28, Issue 38, Pages 13550-13554Publisher
AMER CHEMICAL SOC
DOI: 10.1021/la302550q
Keywords
-
Funding
- CNRS
- INSERM
- University of Strasbourg
- Region Alsace
- Agence Nationale de la Recherche through the Programme Blanc [ANR-10-BLAN-0818]
- Agence Nationale de la Recherche (ANR) [ANR-10-BLAN-0818] Funding Source: Agence Nationale de la Recherche (ANR)
Ask authors/readers for more resources
The design of stimuli-responsive polymer assemblies for the controlled release of bioactive molecules has raised considerable interest these two last decades. Herein, we report the design of mechanically responsive drug-releasing films made of polyelectrolyte multilayers. A layer-by-layer (LbL) reservoir containing biodegradable polyelectrolytes is capped with a mechanosensitive LbL barrier and responds to stretching by a total enzymatic degradation of the film. This strategy is successfully applied for the release in solution of an anticancer drug initially loaded within the architecture.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available