Journal
LANGMUIR
Volume 27, Issue 3, Pages 1175-1180Publisher
AMER CHEMICAL SOC
DOI: 10.1021/la1042734
Keywords
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Funding
- National Natural Science Foundation of China [20925621, 20976054]
- Key Project of Science and Technology for Ministry of Education [107045]
- Shanghai Municipal Education Commission [09ZZ58]
- Fundamental Research Funds for the Central Universities
- Program for Changjiang Scholars and Innovative Research Team in University [IRT0825]
- Shanghai Leading Academic Discipline Project [B502]
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Multifunctional core-shell capsules that triggered release by ultrasound stimulus were one-step fabricated by the coaxial electrospray method. The TiO2 shell suppressed the initial burst release of the paclitaxel. Fe3O4 and graphene quantum dots inside the oil core functioned successfully for magnetic targeting and fluorescence imaging, respectively. Paclitaxel was trigger released when the dual layer of titania shell cracked under the ultrasound stimulation, and the releasing profile could be controlled by the length of applied ultrasound time.
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