Journal
LANGMUIR
Volume 26, Issue 3, Pages 1566-1569Publisher
AMER CHEMICAL SOC
DOI: 10.1021/la904138f
Keywords
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Funding
- National Science Foundation of China [20974084, 30800086]
- NCET
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A new indirect approach to explore sensitive colorimetric sensors toward alpha-amino acids is proposed: the pink solution of 1 and copper ions changed to colorless immediately upon the addition of alpha-amino acids. As the hydrolysis of bovine serum albumin (BSA) with the aid of trypsin produces alpha-amino acids, the complex of 1/Cu2+/BSA could act as a label-free, sensitive, selective sensor toward trypsin. The detection process could be visually observed by naked eyes.
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