Journal
LANGMUIR
Volume 26, Issue 15, Pages 12680-12683Publisher
AMER CHEMICAL SOC
DOI: 10.1021/la101343k
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Funding
- NSF-DMI [0404458]
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We demonstrate immobilization of DNA nanostructures (37 nm x 8 nm) on silicon by a combination of top-down fabrication and bottom-up self-assembly. Anchor lines and pads were defined using electron beam lithography and a cationic molecular monolayer. Individual DNA nanostructures bind in 85% yield onto the anchor pads and can be washed and imaged in air. The strength of the binding interaction between a DNA nanostructure and its anchor pad is at least -43 kJ/mol.
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