Journal
LANGMUIR
Volume 26, Issue 3, Pages 1416-1419Publisher
AMER CHEMICAL SOC
DOI: 10.1021/la903137f
Keywords
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Funding
- National Natural Science Foundation of China [60533010, 30670540, 60874036, 60503002]
- 863 Program of China [2-006AA01Z104]
- Ph.D. Programs Foundation of the Ministry of Education of China [20070001020]
- Postdoctoral Science Foundation of China [20060400344]
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Circular DNA logic gates were constructed on the basis of DNA three-way branch migration. In this logic system, circular DNA was used as a basic work unit and linear single-strand DNA was used as input and output signals. Making use of the circular structure, most of the DNA-specific recognition regions were designed in a single DNA ring. Depending on accurate DNA sequence recognition and highly effective strand displacement, the logic gates yielded correct results. fit addition, the positions of gold nanoparticles (AuNPs) were detected as an alternative approach to determine logic results. Thus, the accurate and tunable control of DNA/AuNPs may be applied widely ill DNA nanotechnology.
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