Journal
LANGMUIR
Volume 26, Issue 2, Pages 1024-1028Publisher
AMER CHEMICAL SOC
DOI: 10.1021/la9041452
Keywords
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Funding
- National Natural Science Foundation of China [20125102, 20421101, 20773053, 50825202, 90306011]
- Chinese Ministry of Education
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A cooperative dual-responsive polypeptide surface switching between superhydrophilic and superhydrophobic states is presented. This macroscopic phenomenon of surface originates from the combination of the cooperative unfolding/aggregation of the poly-L-lysine (PLL) immobilized on the substrate with micro/nanocomposite structure in response to pH and temperature. At pH lower than the pK(a) of PLL (similar to 11.0), PLL mainly adopts a random coil conformation, which corresponds to the superhydrophilic state on the rough surface substrate. Raising the pH to higher than the pK(a) allows the appearance of alpha-helix conformation, which also corresponds to the hydrophilic state. However, heating up the surface at pH higher than the pK(a) destabilizes the alpha-helix conformation and induces the formation of aggregated beta-sheet structures, which represents the superhydrophobic state. Lowering the pH and temperature simultaneously switches a reversible conversion from superhydrophobic to superhydrophobic states. In the switching process, the hydrophobicity and hydrophilicity can be memorized due to the cooperative pH and temperature stimuli-induced unfolding/aggregation behaviors or PLL. This provides a new exciting prospect for understanding Surface propel-ties of polypeptides and the design of smart material surfaces with potential applications in nanodevices, bioseparation, and biosensors.
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